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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13C
All Species:
13.03
Human Site:
S2220
Identified Species:
35.83
UniProt:
Q709C8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q709C8
NP_001018098.1
3753
422390
S2220
L
T
I
M
A
A
L
S
P
K
T
K
E
D
G
Chimpanzee
Pan troglodytes
XP_510458
3836
431033
S2303
L
T
I
M
A
A
L
S
P
K
T
K
E
D
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851912
3629
408076
S2219
M
T
I
M
A
A
M
S
P
K
T
K
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX70
3748
420070
S2215
M
T
I
M
A
A
M
S
P
K
T
K
E
D
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511058
3801
426177
K2258
V
T
I
M
A
A
M
K
P
K
T
K
E
D
D
Chicken
Gallus gallus
XP_001233000
3758
422392
X2219
V
T
I
M
A
A
X
X
X
X
X
X
X
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922767
3699
412330
A2196
I
T
I
T
A
A
M
A
P
K
P
K
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192977
2470
271032
V1082
W
S
L
S
V
N
V
V
K
N
D
D
L
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07878
3144
357831
L1755
L
G
G
L
R
F
I
L
I
G
D
V
H
E
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
87
N.A.
86.4
N.A.
N.A.
77.2
68.7
N.A.
59.6
N.A.
N.A.
N.A.
N.A.
24.1
Protein Similarity:
100
97.4
N.A.
92
N.A.
93.3
N.A.
N.A.
87.6
82.9
N.A.
76.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
100
N.A.
80
N.A.
80
N.A.
N.A.
73.3
33.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
N.A.
N.A.
86.6
46.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
78
78
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
23
12
0
56
34
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
67
34
23
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
12
0
0
0
0
0
0
12
0
0
0
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
12
0
78
0
0
0
12
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
12
67
0
67
0
0
0
% K
% Leu:
34
0
12
12
0
0
23
12
0
0
0
0
12
12
12
% L
% Met:
23
0
0
67
0
0
45
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
67
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
0
12
0
0
0
45
0
0
0
0
0
0
0
% S
% Thr:
0
78
0
12
0
0
0
0
0
0
56
0
0
0
0
% T
% Val:
23
0
0
0
12
0
12
12
0
0
0
12
0
0
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _